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Dr. Karim Rastegar, M.D., Ph.D.

Dr. Karim Rastegar was born in 1947 in Shiraz, Iran, into a moderately religious family. From an early age he was drawn to the Qurʾān, spending his secondary school years in deep study of the text and its meaning — a formation that would shape the entire arc of his intellectual life.

As a medical student at Pahlavi University in the mid-1960s, Dr. Rastegar became convinced that meaningful social reform required a rigorous understanding of the laws governing human society. This conviction drew him into political activism and, for a decade, into membership in an Islamic revolutionary organization. It was during years of political struggle, imprisonment, and solitary confinement that his understanding of Islam underwent a fundamental transformation. Confronting the limitations of Marxist theory — which dominated the ideological landscape of the Iranian left — and finding that the prevailing interpretations of Islam offered no adequate scientific framework for understanding society or nature, he turned instead to the Qurʾān itself.

In solitary confinement, with a copy of the Qurʾān as his only companion, Dr. Rastegar began reading the text differently — not as a collection of legal prescriptions or devotional literature, but as a book that contained, in its own distinctive language, a coherent description of the physical and social world. He emerged from that experience with a research program that would occupy the rest of his life.

After completing his medical degree, Dr. Rastegar pursued postgraduate training in psychiatry, then traveled to the United Kingdom to undertake doctoral research in neuroscience at University College London, graduating with a Ph.D. in 1990. His research focused on the neurophysiological basis of the soul — a question he had carried from the Qurʾān into the laboratory. Working with experimental models of hippocampal function and memory, he developed an empirical framework for understanding how the brain and the soul, as the Qurʾān describes them, relate to one another. His thesis was awarded one of UCL's prizes for best research of the year.

Returning to Iran, Dr. Rastegar joined the faculty of Shiraz University of Medical Sciences, where he served as Associate Professor of Neurophysiology and Head of the Department of Physiology from 2001 to 2009. He continued clinical practice as a consultant psychiatrist for over two decades, while simultaneously pursuing the larger scholarly project that had begun in that prison cell decades earlier. He retired from the university in 2020.

The result of that lifelong inquiry is the Qurʾānology series — twenty volumes covering cosmology, physics, earth sciences, the origin and evolution of life, neuroscience, psychology, social theory, and theology. All volumes are complete in Persian. English translations are being prepared under the auspices of the Quranic Sciences Institute. The first volume, Fundamentals of Qurʾānology, was submitted to Brill Publishing in April 2026.

Dr. Rastegar's work does not seek to harmonize the Qurʾān with science, nor to subordinate scientific findings to religious authority. His argument is more precise: that the Qurʾān encodes empirical truths in a form designed to be understood progressively as human knowledge advances — and that reading it carefully, in light of what we now know, reveals a coherent and scientifically serious account of the world.

Academic Position
Associate Professor of Neurophysiology (Retired 2020)
Shiraz University of Medical Sciences
Doctoral Training
Ph.D. Neuroscience
University College London, 1985–1990
Clinical Practice
Consultant Psychiatrist
Shiraz, Iran — 1991–2020
Research Focus
Neurophysiology · Neuroscience of memory
Qurʾānic hermeneutics · Religion and science

Selected Publications — Qurʾānology Series

  • Vol. 1 — Qurʾān Fundamentals of Qurʾānology: A Methodological Approach to Meaning, Miracle, and the Epistemology of Guidance in the Qurʾān
    Submitted to Brill Publishing — April 2026
  • Vol. 2 — Human Sciences A Treatise on the Soul: A Scientific Inquiry into the Existence of the Soul and Its Implications for Human Agency and Accountability
    English Translation Complete — 2022
  • Vol. 3 — Earth Sciences The Seven Heavens
    English First Draft Complete — 2025
  • Vol. 4 — Science and Religion The Relationship Between Science and Religion
  • Vols. 5–6 — Physics and Cosmology Qurʾān and the Physical World (The Book of the Seat), Vols. 1–2
  • Vol. 7 — Earth Sciences The Formation and Evolution of the Solar System: A Qurʾānic View
  • Vols. 8–9 — Life Sciences The Origin of Life: A Qurʾānic View · Life and Its Evolution: A Qurʾānic View
  • Vols. 10–12 — Social Sciences Islam and Society: A Preface · Islam and Society · Islamic Ideology
  • Vols. 13–20 — Human Sciences, Theology, Eschatology The Structure and Function of the Brain · Psychology: A Qurʾānic View · Theism · Signs and Miracles · Parallel Universes · The Other World · The Resurrection Day · Faith in the Hereafter

Peer-Reviewed Research

In addition to the Qurʾānology series, Dr. Rastegar has authored 15 peer-reviewed articles in international journals, primarily in the areas of hippocampal neurophysiology, memory and learning, neurodegeneration, and the effects of pharmacological agents on spatial memory. His experimental research was conducted at Shiraz University of Medical Sciences in collaboration with national and international colleagues.